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Our Top Pick
9.7/10 our score
Best Flea Medicine For Cats
Frontline Plus Flea and Tick Treatment for Cats
Advantage II 6-Dose Large Cat Flea Prevention, Flea Prevention for Cats, Over 9 Pounds
Advantage II Small Cat Flea Treatment, 4-Dose Small Cat Flea Prevention, 5-9 Pounds
PetArmor for Cats, Flea & Tick Treatment for Cats (Over 1.5 Pounds), Includes 3 Month Supply of Topical Flea Treatments
Hartz UltraGuard Topical Flea & Tick Prevention for Cats and Kittens – 3 Monthly Treatments
Cheristin for Cats Topical Flea Prevention – Starts Killing Fleas in 30 Minutes, 3 Doses
CAPACTION Fast-Acting Oral Flea Treatment for Cats (2-25 lbs), 6 Doses, 11.4 mg
Amazon Brand – Solimo Flea and Tick Topical Treatment for Cats (over 1.5 pounds), 6 Doses
Capstar Fast-Acting Oral Flea Treatment for Cats, 6 Doses, 11.4mg (2-25 Lbs)
TevraPet Actispot II Flea Treatment for Small and Medium Cats 5-9 lbs | 6 Doses | Powerful Prevention and Control, Clear
1. Frontline Plus Flea and Tick Treatment for Cats
- Waterproof flea and tick treatment for cats and kittens: Frontline Plus for Cats provides waterproof, fast-acting, long-lasting flea and tick treatment and control for your cat. This product is approved for use on cats and kittens 1.5 lbs and over.
- Break the flea life cycle with frontline: Frontline flea and tick treatment for cats kills adult fleas plus flea eggs and larvae to stop existing infestations and prevent establishment of new infestations.
- Kills fleas and ticks: Frontline flea and tick treatment for cats kills fleas, flea eggs, lice, and ticks. This flea and tick treatment kills ticks, including those that may transmit Lyme disease.
- Trusted flea and tick protection for cats: Frontline Plus for Cats has been trusted by veterinarians for nearly 20 years. Made with 2 tough killing ingredients, fipronil and (S)-methoprene – one to kill adult fleas and ticks and the second to kill flea eggs and larvae – this fast-acting, long-lasting protection provides flea and tick control for cats and kittens 8 weeks and older.
- Lasting flea and tick protection: Frontline’s long-lasting formula is stored in the oil glands of the cat’s skin to give non-stop flea and tick protection for a full 30 days. Frontline flea and tick treatment for cats works non-stop for a full 30 days. A 3-dose supply lasts for 3 months.
2. Advantage II 6-Dose Large Cat Flea Prevention, Flea Prevention for Cats, Over 9 Pounds
- 6-month supply of advantage II topical large cat flea prevention
- Easy-to-apply and pre-measured flea treatment application tubes, fragrance-free and waterproof after 24 hours
- Advantage II large cat flea prevention kills fleas through contact, meaning fleas don’t have to bite your cat in order to die.Avoid contact with eyes or clothing
- Starts working within 12 hours and protects your cat for up to 30 days. Kills fleas in multiple life stages, Eggs, larvae and adults to break the flea life cycle
- Vet recommended, fragrance free and designed specifically to treat and prevent fleas on cats
3. Advantage II Small Cat Flea Treatment, 4-Dose Small Cat Flea Prevention, 5-9 Pounds
- Contains four one-month applications of Bayer Advantage II topical flea prevention and treatment for small cats 5-9 pounds
- Advantage II works through contact, so fleas don’t have to bite your cat to die
- This effective flea treatment kills fleas in multiple life stages — eggs, larvae and adults — to break the flea life cycle
- Easy-to-apply cat flea treatment starts working within 12 hours and protects for up to 30 days
- Advantage II is vet-recommended, fragrance-free and designed specifically to treat and prevent fleas on cats
4. PetArmor for Cats, Flea & Tick Treatment for Cats (Over 1.5 Pounds), Includes 3 Month Supply of Topical Flea Treatments
- CAT FLEA AND TICK CONTROL: SENTRY Fiproguard topical flea and tick prevention for cats kills fleas, ticks and chewing lice for up to 30 days.
- VET QUALITY FORMULA: SENTRY Fiproguard is a vet-quality formula flea treatment that contains the active ingredient fipronil.
- FOR KITTENS AND CATS: PetArmor topical flea treatment for cats and kittens 8 weeks and older for up to 30 days after application and helps prevents infestations of adult fleas.
- FLEA AND TICK PREVENTION: PetArmor for cats helps you protect your furry family member from the diseases fleas and ticks carry, including deer ticks that may transmit Lyme disease.
- INCLUDES: Three (3) 0.017 fl. oz. waterproof topical applications for cat flea and tick control. For best results, apply flea & tick treatment for cats directly to dry skin on your cats back, between the shoulder blades, on a monthly basis.
5. Hartz UltraGuard Topical Flea & Tick Prevention for Cats and Kittens – 3 Monthly Treatments
- Topical drop formula kills fleas and deer ticks
- Includes 3 monthly treatments in easy to apply, single dose tubes
- Repels mosquitoes for 18 days
- For use on cats and kittens 12 weeks and older weighing 5 pounds and over
6. Cheristin for Cats Topical Flea Prevention – Starts Killing Fleas in 30 Minutes, 3 Doses
- Topical flea treatment and prevention designed just for cats
- Long-lasting treatment protects against fleas through 6 weeks
- One-size-fits-all for all cats and kittens over 1. 8 lbs. and 8 weeks old
- Rounded tip applicator for comfortable, easy application
- Starts killing fleas in only 30 minutes and kills 98-100% of fleas in 12 hours in a controlled study
7. CAPACTION Fast-Acting Oral Flea Treatment for Cats (2-25 lbs), 6 Doses, 11.4 mg
- FAST-ACTING: One oral flea tablet starts killing fleas within 30 minutes of administration.
- SAFE TO USE: This oral flea medication is safe for kittens and cats from 2-25 lbs. 4 weeks and older, when used as directed.
- TREAT RE-INFESTATIONS FAST: If your pet gets re-invested with fleas simply apply another dose as often as once a day. CapAction Flea Pills are even safe for use on pregnant or breeding cats.
- EASY TO USE: Without the mess and rubbing off of a flea and tick topical treatment and without the need of a veterinarian prescription this cat flea tablet is administered orally to kill adult fleas fast.
- KILL FLEAS EFFICIENTLY: CapAction flea treatment has 6 doses and kills adult fleas that may cause allergy dermatitis.
8. Amazon Brand – Solimo Flea and Tick Topical Treatment for Cats (over 1.5 pounds), 6 Doses
- Solimo topical flea and tick prevention for cats kills fleas, flea eggs, flea larvae, ticks, and chewing lice for up to 30 days after application.
9. Capstar Fast-Acting Oral Flea Treatment for Cats, 6 Doses, 11.4mg (2-25 Lbs)
- FAST-ACTING FLEA TREATMENT: One oral flea tablet starts killing fleas within 30 minutes.
- TACKLE FLEA INFESTATIONS FAST: Give Capstar oral flea treatment and watch dead fleas fall off your pet.
- TREAT RE-INFESTATIONS FAST: If your pet gets re-invested with fleas, simply give another dose as often as once a day.
- WITHOUT A VET PRESCRIPTION: Flea treatment without needing a veterinarian prescription, administer this cat flea tablet orally to kill adult fleas fast.
- KILL ADULT FLEAS: Capstar oral flea treatment tablets (11.4 mg) are safe for cats and kittens from 2-25 lbs., four (4) weeks and older.
10. TevraPet Actispot II Flea Treatment for Small and Medium Cats 5-9 lbs | 6 Doses | Powerful Prevention and Control, Clear
- POWERFUL FLEA KILLING TREATMENT FOR SMALL AND MEDIUM CATS: TevraPet Actispot II is a waterproof topical for cats that kills fleas, flea eggs, and flea larvae for up to 30 days after each application
- VET APPROVED FORMULA: TevraPet Actispot II uses Imidacloprid and Pyriproxyfen – the same safe and effective active ingredients found in Advantage II – but costs far less. Every cat deserves veterinarian quality treatment, Actispot II helps you provide the same level of care without breaking the bank
- FAST ACTING AND LONG-LASTING WITH NO BITING REQUIRED: TevraPet Actispot II REPELS and KILLS fleas on contact, without your cat being exposed to bites. Begins killing within 24 hours of application, and starts repelling immediately. Other oral flea tablets, pills, and chews require that your pet is bitten by a pest before the meds can start working, potentially exposing your kitty to flea borne diseases
- BREAK THE CYCLE, PREVENT REINFESTATION: Unlike other flea medications that only temporarily control fleas, Actispot II flea treatment stops infestations dead in their tracks by effectively breaking the flea life cycle. Actispot II safely kills flea eggs and larvae to prevent re-infestation so your cat can get on with napping in the sun and strolling or stalking! through the garden
- EASY-TO-USE, MADE IN AMERICA: We proudly make every dose of Actispot II here in the USA and rigorously test for quality and potency. Each package comes with six 6 easy to apply, fully waterproof topical applications that ensure your friend has safe and reliable flea protection and control for up to six 6 months
- Age range description: all life stages